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ea0056p308 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2018

Soluble ST2, a promising cardiovascular biomarker, is associated with parameters of glucose and bone metabolism in subjects at cardiovascular risk

Francic Vito , Gaksch Martin , Schwetz Verena , Trummer Christian , Pandis Marlene , Aberer Felix , Grubler Martin , Verheyen Nicolas D , Marz Winfried , Pieber Thomas R , Tomaschitz Andreas , Pilz Stefan , Obermayer-Pietsch Barbara

Introduction: Soluble ST2 (sST2) is the truncated soluble form of the ST2 receptor in the circulation. It is a decoy receptor of IL-33 and thereby inhibits the effects of IL-33/ST2 signaling. Elevated levels of sST2 have been associated with various adverse cardiovascular outcomes. Recently, potential associations of sST2 with obesity and type 2 diabetes mellitus (T2DM) have been described in the general population. In this study, we determined possible cross-sectional associa...

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Soluble ST2, a promising cardiovascular biomarker, is associated with parameters of glucose and bone metabolism in subjects at cardiovascular risk

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